What is Hyaluxelle®?

Hyaluxelle® is a non-hormonal injectable treatment containing hyaluronic acid. It is designed to support the hydration and condition of the vulvovaginal tissues and is used for symptoms associated with vulvovaginal atrophy.

Vulvovaginal symptoms are particularly common around and after menopause, when falling oestrogen levels can affect the tissues around the vagina and vulva. This can cause dryness, burning, itching and discomfort, as well as pain during sexual intercourse.

These symptoms can have a significant impact on comfort, intimacy and quality of life — but they are not something you simply have to put up with.

What symptoms can Hyaluxelle® help with?

Hyaluxelle® is indicated for adult women experiencing symptoms associated with vulvovaginal atrophy, including:

  • Vaginal or vulval dryness
  • Burning or irritation
  • Non-infectious itching
  • Discomfort around the vaginal opening
  • Pain during sexual intercourse

The treatment may help improve tissue hydration and thickness and reduce symptoms such as burning, itching and discomfort. Clinical studies have also reported improvements in sexual function and quality of life.

Why does vaginal dryness happen?

Vaginal dryness and other vulvovaginal symptoms can occur when oestrogen levels fall. This is particularly common during perimenopause and menopause, but symptoms can also occur following surgical menopause or some medical treatments.

The tissues can become thinner, less elastic and less well lubricated. This can lead to discomfort, irritation and pain during sex.

Genitourinary syndrome of menopause (GSM) can affect more than just the vagina. Some women also experience urinary symptoms, including urgency, frequency or recurrent urinary tract infections.

How does Hyaluxelle® work?

Hyaluxelle® contains high- and low-molecular-weight hyaluronic acid.

Hyaluronic acid naturally occurs within the body and has an important role in hydration and tissue structure. Hyaluxelle® is designed to improve hydration and support the condition of atrophic vulvovaginal tissues.

The treatment is administered into the vulvovaginal tissues using a very small needle by a trained clinician.

What does the treatment involve?

At West Wales Women’s Wellbeing, treatment starts with a consultation and assessment.

We will talk through your symptoms, medical history and previous treatments to establish whether Hyaluxelle® is an appropriate option for you.

If treatment is suitable, the recommended initial course consists of two treatment sessions, approximately 30 days apart. A review is then recommended to assess your response to treatment.

A local anaesthetic cream may be recommended before the injections to help make the procedure more comfortable.

Is Hyaluxelle® a hormone treatment?

No.

Hyaluxelle® is a non-hormonal treatment containing hyaluronic acid.

This makes it a potential option for women who are looking for a non-hormonal approach to vulvovaginal symptoms. However, whether it is appropriate for you depends on the cause of your symptoms and your individual circumstances.

There are several treatment options for genitourinary symptoms of menopause, including vaginal oestrogen, moisturisers and lubricants. Your clinician can talk through these options with you and help you decide what may be most appropriate.

What can I expect after treatment?

Most women tolerate the treatment well. Temporary effects around the injection sites can occur, including:

  • Mild soreness or pain
  • Redness
  • Swelling
  • Bruising
  • Itching
  • A sensation of warmth

These effects generally settle within a short period. You should let your clinician know if you experience any unexpected or persistent symptoms.

For the first few days following treatment, you should avoid sexual intercourse, cycling and horse riding, as well as saunas or Turkish baths. Exposure to UV light should also be avoided for several days.

Who is Hyaluxelle® not suitable for?

Hyaluxelle® should not be used during pregnancy or breastfeeding. It is also not suitable for women with certain autoimmune or collagen disorders, or known hypersensitivity to the product’s components.

A full medical history and assessment will be undertaken before treatment.

Is Hyaluxelle® right for me?

Vaginal dryness and discomfort can have a number of causes, so it is important to establish what is contributing to your symptoms before deciding on treatment.

At West Wales Women’s Wellbeing, we can assess your symptoms and discuss the different treatment options available, including hormonal and non-hormonal approaches.

You don’t have to feel embarrassed about talking about vaginal dryness, painful sex or vulvovaginal discomfort. These are common symptoms and we’re here to help you find an appropriate treatment approach.

If you’re experiencing vaginal dryness, burning, itching or discomfort during sex, our consultant-led menopause and gynaecology service can offer assessment and personalised advice.

Hyaluxelle® treatment is available following consultation and assessment with our Consultant Gynaecologist to establish whether it is appropriate for you.