Author: WWWW

  • ➡️Is My Ovarian Cyst Something to Worry About? Let’s Talk It Through.

    Recently, I’ve had a number of conversations with women who have been told that they have an ovarian cyst or an adnexal mass.

    Understandably, this can cause anxiety.

    The questions are often very similar:

    “Could this be cancer?”

    “My CA125 is raised. Should I be worried?”

    “Should I have an HE4 test?”

    “What are RMI and ROMA?”

    Because I’ve found myself having these conversations increasingly often, I wanted to explain some of the things I look at when assessing an ovarian cyst or adnexal mass.

    The first thing to say is reassuring:

    Most ovarian cysts and adnexal masses are benign.

    However, identifying which masses are reassuring, which need surveillance and which require further investigation or specialist referral is extremely important.

    At West Wales Women’s Wellbeing, our approach is based on a simple principle:

    We don’t rely on one thing.

    A blood test, an ultrasound feature or a risk score should not be considered in isolation.

    Instead, we bring together your clinical history, menopausal status, specialist in-house ultrasound, recognised ultrasound terminology, risk models, pattern recognition and blood biomarkers where appropriate.

    The aim is to build a holistic assessment of your individual risk and, importantly, decide what should happen next.

    What is an adnexal mass?

    The term adnexal mass can sound worrying, but it simply describes an abnormality arising from the ovary, fallopian tube or surrounding tissues.

    There are many possible causes.

    These include simple ovarian cysts, haemorrhagic cysts, endometriomas associated with endometriosis, dermoid cysts and many other benign conditions.

    A much smaller proportion will represent borderline or malignant disease.

    So finding an ovarian mass does not mean that you have ovarian cancer.

    The important question is what that particular mass represents and how confident we can be about its nature.

    It starts with the ultrasound

    A specialist gynaecological ultrasound is at the heart of our assessment.

    Modern ultrasound can tell us considerably more than simply whether a cyst is present or how large it is.

    We assess the morphology, or architecture, of the mass in detail.

    For example:

    • Is it a simple fluid-filled cyst?
    • Is it unilocular or multilocular?
    • Are there solid components?
    • Are papillary projections present?
    • What does the cyst wall look like?
    • What pattern of blood flow is present?
    • Is there free fluid?
    • What does the other ovary look like?
    • Are there other findings within the pelvis?

    Just as importantly, we consider how these findings fit together.

    Ultrasound terminology and pattern recognition

    We use standardised ultrasound terminology, including internationally recognised approaches developed by the International Ovarian Tumor Analysis (IOTA) group.

    Why does terminology matter?

    Because describing an ovarian mass consistently allows us to move beyond vague terms such as “complex ovarian cyst”.

    A detailed description of the morphology of a mass helps us understand what it is likely to represent and enables meaningful risk assessment.

    Alongside this structured assessment, specialist ultrasound also involves pattern recognition.

    Certain ovarian masses can have characteristic ultrasound appearances. The combination of their shape, internal structure, echogenicity and vascular pattern can provide important clues about their likely pathology.

    Pattern recognition is therefore an important part of specialist gynaecological ultrasound, particularly when combined with validated assessment models.

    The IOTA ADNEX model

    Where appropriate, we can use the IOTA ADNEX model, which stands for Assessment of Different NEoplasias in the adneXa.

    ADNEX combines specific clinical and ultrasound features to estimate the probability that an adnexal mass is benign or malignant.

    One of its strengths is that it goes beyond a simple “low risk/high risk” answer. The model can provide estimates across different categories of disease, helping add further structure to the ultrasound assessment.

    But the same principle applies here as it does to blood tests:

    ADNEX is a tool to support clinical assessment, not replace it.

    We interpret the result alongside the actual ultrasound images, pattern recognition, your history and other relevant investigations.

    What about CA125?

    CA125 is probably the blood test most commonly associated with ovarian cancer.

    It can be extremely useful, but it is also frequently misunderstood.

    CA125 is not, by itself, a test for ovarian cancer.

    Some ovarian cancers produce increased amounts of CA125, but many benign conditions can also cause it to rise.

    These include conditions such as endometriosis, fibroids, menstruation and pelvic inflammation.

    This is particularly important in premenopausal women.

    Conversely, a normal CA125 does not completely exclude ovarian malignancy.

    So when somebody comes to clinic concerned about an abnormal CA125, we don’t simply look at whether the number is inside or outside the laboratory reference range.

    We ask a much more useful question:

    What does this CA125 result mean in the context of this woman’s ultrasound, symptoms, menopausal status and overall clinical picture?

    What is the RMI?

    The Risk of Malignancy Index (RMI) is an established method of estimating the risk associated with an ovarian mass.

    It combines three pieces of information:

    RMI = Ultrasound score × Menopausal status × CA125

    This is important because the RMI does not rely on the CA125 result alone. It incorporates specific ultrasound features and whether a woman is pre- or postmenopausal.

    The resulting score can help determine whether further investigation or referral into a specialist pathway is appropriate.

    However, an RMI remains a risk assessment, not a diagnosis.

    A high RMI does not mean that someone definitely has ovarian cancer, and a low RMI cannot provide an absolute guarantee that a mass is benign.

    It is another piece of the overall picture.

    What is HE4?

    HE4 stands for Human Epididymis Protein 4.

    Like CA125, HE4 is a biomarker that can be measured in the blood. Levels may be increased in some epithelial ovarian cancers.

    HE4 behaves somewhat differently from CA125, which means that in selected situations it can provide additional information.

    This can be particularly useful when CA125 is difficult to interpret in isolation.

    But HE4 has limitations too.

    Its level can be affected by factors including age and kidney function, and an elevated HE4 does not diagnose ovarian cancer.

    It needs context.

    What is ROMA?

    This brings us to another acronym that women are increasingly encountering: ROMA.

    ROMA stands for the Risk of Ovarian Malignancy Algorithm.

    It combines:

    CA125 + HE4 + menopausal status

    These factors are used within an algorithm to classify the risk associated with an adnexal mass.

    This is quite different from the RMI.

    RMI uses:

    Ultrasound + CA125 + menopausal status

    ROMA uses:

    HE4 + CA125 + menopausal status

    ROMA therefore adds information from a second biomarker, HE4, but does not directly incorporate the detailed ultrasound appearance of the mass.

    ROMA is also not an ovarian cancer screening test for women who do not have an adnexal mass.

    And, importantly, a higher-risk ROMA result does not mean that ovarian cancer has been diagnosed.

    It tells us something about risk.

    RMI, ROMA or ADNEX: which is best?

    This is perhaps the wrong question.

    Each looks at the problem from a slightly different angle.

    RMI combines a relatively simple ultrasound score with CA125 and menopausal status.

    ROMA combines two biomarkers, CA125 and HE4, with menopausal status.

    ADNEX uses much more detailed information about the ultrasound appearance of the mass alongside clinical information, with CA125 incorporated where appropriate.

    And then there is the clinician’s pattern recognition, interpreting what the mass actually looks like in real time.

    Rather than placing all our confidence in one number, at WWWW we prefer to ask:

    Do all the different pieces of information tell a consistent story?

    That is a much more useful clinical question.

    Putting the pieces together

    Our comprehensive adnexal mass assessment therefore brings together several different layers of information.

    Your story

    Your symptoms, age, menstrual or menopausal status, medical and family history, previous imaging and how the mass was discovered.

    Specialist ultrasound

    A detailed in-house gynaecological ultrasound assessing the morphology and vascularity of the mass and the remainder of the pelvis.

    Standardised terminology

    Using recognised ultrasound terminology so that the features of the mass are described systematically rather than simply labelling it a “complex cyst”.

    Pattern recognition

    Considering whether the combination of ultrasound appearances suggests a recognisable benign or malignant pattern.

    Validated risk assessment

    Using models such as IOTA ADNEX or RMI where appropriate.

    Biomarkers

    Interpreting CA125 and, in selected circumstances, additional markers such as HE4 and ROMA within the wider clinical picture.

    It is the combination that matters.

    What happens after the assessment?

    The purpose of all of this is not simply to generate another score.

    It is to answer the question that actually matters:

    What should we do next?

    For some women, the ultrasound appearances are reassuring and no further investigation may be required.

    For others, repeating an ultrasound after an appropriate interval may be recommended.

    Sometimes additional blood tests, further imaging or another specialist opinion is helpful.

    And occasionally the safest recommendation is referral into an NHS specialist gynaecology or gynaecological oncology pathway.

    A good assessment should therefore provide more than a description of an ovarian cyst.

    It should provide a clear clinical plan.

    “So, should I worry about my ovarian cyst?”

    In most cases, an ovarian cyst will ultimately prove to be benign.

    But understandably, being told that you have an ovarian mass can create considerable uncertainty, particularly if you have also received an abnormal blood result.

    Our approach is not to provide reassurance based on one number alone.

    Nor do we believe that simply ordering more blood tests necessarily provides a better answer.

    Instead, we bring together specialist ultrasound, recognised ultrasound terminology, pattern recognition, validated risk models such as ADNEX and RMI, and biomarkers including CA125 and, where appropriate, HE4 and ROMA.

    This allows us to develop a more complete, individualised assessment of risk.

    Because ultimately the most useful question isn’t:

    “Is my CA125 normal?”

    or:

    “What is my ROMA score?”

    It is:

    “When we put everything together, what does my ovarian mass most likely represent, what is my individual risk, and what should happen next?”

    That is the question a comprehensive adnexal mass assessment should help answer.

  • ➡️HPV Self-Sampling: What Does the New Home Cervical Screening Test Mean for Women in Wales?

    We’ve been asked by a number of women what we make of the news about HPV self-sampling, particularly those living here in Wales, so we thought it would be helpful to explain what’s actually happening, what the evidence tells us, and what it means for you.

    You may have seen the news that women in England are now being offered the option of doing an HPV test at home.

    For some women, this will be very welcome news.

    The thought of making an appointment, having a speculum examination and having a sample taken from the cervix can be a significant barrier to cervical screening. For some, it may be anxiety and uncertain. For others, it may be a previous experience or trauma. There can also be very practical barriers – finding an appointment, taking time off work, arranging childcare or simply finding the time to attend.

    So the idea of being able to take your own sample at home sounds very appealing.

    But if you live in Wales, there is an important distinction to make.

    The rollout you may have seen in the news is happening in England. Wales is developing its own self-sampling programme, which is expected to roll out later in 2026.

    So what exactly is happening, what does the evidence tell us, and what does it mean if you live in Wales?

    What is HPV self-sampling?

    Let’s start with the basics.

    HPV stands for human papillomavirus. It is an extremely common virus, and most people will come into contact with it at some point in their lives.

    Certain types of HPV, known as high-risk HPV, can cause changes to the cells of the cervix. If these changes persist and are not identified and managed, they can, over time, develop into cervical cancer.

    This is why cervical screening now looks for high-risk HPV.

    In Wales, HPV testing has been the primary cervical screening test since 2018.

    With self-sampling, instead of a healthcare professional taking a sample from your cervix using a speculum, you collect a sample yourself from inside the vagina using a swab.

    That sample is then sent to a laboratory where it is tested for high-risk HPV.

    It is important to understand that this is an HPV test. It isn’t quite the same thing as doing a traditional cervical screening sample yourself.

    So, is self-sampling as good as having a cervical screening test?

    This is one of the obvious questions.

    The evidence so far is encouraging.

    Research has shown that HPV testing using self-collected vaginal samples can be an effective way of detecting high-risk HPV, and women generally find self-sampling acceptable.

    One of the most important UK studies has been the YouScreen study in England. It looked at offering HPV self-sampling to people who had not attended cervical screening and found that offering self-sampling could increase participation, including among groups who have historically been less likely to take part.

    And this is really the key point.

    The purpose of self-sampling isn’t necessarily to replace the way everyone currently has their cervical screening.

    It is about finding another way to reach people who might otherwise not be screened at all.

    That could make a very real difference.

    Who is being offered self-sampling in England?

    The rollout in England has now begun, but it is not currently a replacement for routine cervical screening for everyone.

    It is being introduced in phases and is initially aimed at women and people with a cervix aged 30 to 65 who have not attended cervical screening following previous invitations.

    It is an invitation-only programme.

    So this isn’t currently a situation where everyone is going to receive a home testing kit instead of their usual screening appointment.

    The aim is to reach people who are under-screened – particularly those who have repeatedly not taken up their invitations.

    And I think that makes a lot of sense.

    If you are already attending your cervical screening appointments regularly, there is currently no reason to assume that you need to change how you are screened simply because self-sampling is now available.

    What happens if HPV is detected?

    This is really important.

    A self-sample can tell us whether high-risk HPV is present.

    It cannot tell us whether there are abnormal cells on the cervix.

    So if high-risk HPV is detected, you will need further assessment.

    You would be invited for a follow-up cervical screening appointment where a trained healthcare professional takes a sample from the cervix so that the cervical cells can be examined.

    Depending on the result of that sample, you may then need further monitoring or referral for assessment such as colposcopy.

    So self-sampling does not necessarily mean avoiding a clinical examination altogether.

    It is another way of getting people into the screening pathway.

    And if you receive a positive HPV result from a self-sample, it is really important that you attend the follow-up appointment when invited.

    What happens if HPV isn’t detected?

    This is the reassuring part.

    If high-risk HPV isn’t detected, your risk of developing significant cervical cell changes in the near future is very low.

    In Wales, if HPV isn’t found during routine screening, you are generally invited for screening again in five years.

    That longer interval can sometimes seem surprising, but it reflects how much cervical screening has changed.

    We now know that testing for high-risk HPV is a very effective way of identifying people who are at increased risk of developing cervical cell changes.

    So a negative HPV result is genuinely reassuring.

    Why are we introducing self-sampling?

    Because not everyone finds cervical screening easy.

    And I think we need to acknowledge that.

    As a gynaecologist, I see women who are anxious about cervical screening for lots of different reasons.

    Some have experienced pain.

    Some have had a previous difficult examination.

    Some have experienced trauma.

    Some feel embarrassed.

    Some find intimate examinations particularly difficult because of sensory sensitivities or anxiety.

    And for others, it is simply the practicalities.

    Work.

    Childcare.

    Transport.

    Appointments that don’t fit around their lives.

    None of these things mean someone doesn’t care about their health.

    Sometimes the system simply hasn’t made it easy for them to take part.

    Self-sampling removes some of those barriers.

    You can collect the sample yourself, in your own home, without a speculum examination.

    For some women, that could be the difference between being screened and not being screened at all.

    Could self-sampling increase cervical screening uptake?

    This is probably the most exciting part of the evidence.

    Studies have shown that offering HPV self-sampling can encourage some people who have previously not attended cervical screening to participate.

    The UK National Screening Committee reviewed the evidence and recommended that cervical screening programmes across the UK could offer self-sampling to people who never or rarely attend routine screening. It specifically identified the potential to increase participation and reduce health inequalities.

    And that is important because cervical screening only works if people take part.

    A screening test sitting unopened at home or an appointment that is repeatedly missed cannot prevent cervical cancer.

    If self-sampling makes screening accessible to someone who has previously struggled to attend, that is a very positive thing.

    So what does this mean if you live in Wales?

    This is where things get a little confusing because much of the news you are currently seeing is about England.

    Wales has its own cervical screening programme and its own arrangements.

    The UK National Screening Committee’s recommendation applies across the UK, but each nation’s screening programme decides how it will implement self-sampling.

    The Welsh Government confirmed in March 2026 that Cervical Screening Wales is developing an at-home, self-collected screening model, with rollout planned for later in 2026.

    The initial focus will be on women who rarely or never take up their offer of cervical screening.

    So, if you live in Wales:

    Self-sampling is coming.

    But the English rollout does not mean that you can currently order an English NHS kit if you live in Wales.

    The Welsh programme will set out how the service will work here, who will initially be eligible and how the kits and follow-up pathway will operate.

    Does this mean I should wait for self-sampling?

    No.

    This is probably the most important message I want people to take away from all of this.

    If you have received an invitation for cervical screening, please go.

    Don’t put off your screening appointment because you’ve heard that home testing is coming.

    The initial self-sampling programme is being introduced specifically to try to reach people who are currently under-screened.

    It isn’t a reason for people who already attend screening to stop doing so.

    Cervical screening remains one of the most effective ways we have of preventing cervical cancer.

    What if I’ve avoided cervical screening because I’m worried about the examination?

    Please don’t feel embarrassed about saying that.

    As a gynaecologist, I would much rather know that someone is anxious, has experienced pain previously, has had a traumatic experience, or simply doesn’t feel comfortable with a speculum examination.

    There are things that can sometimes help.

    You can talk to the healthcare professional beforehand.

    You can ask questions.

    You can ask for a smaller speculum where appropriate.

    You can ask them to explain what they are doing before they do it.

    You can agree on a signal to stop.

    And you can tell them if you’ve had a previous difficult experience.

    A cervical screening appointment should not feel like something that is simply being done to you.

    You should feel involved in what is happening.

    And if self-sampling eventually makes screening more accessible for you, that is exactly what it is there to do.

    What if I’ve had the HPV vaccine?

    You should still attend cervical screening.

    The HPV vaccine provides excellent protection against the HPV types that cause many cervical cancers, and it has already had a significant impact on HPV infection and cervical disease.

    But it doesn’t protect against every HPV type that can cause cervical cancer.

    So even if you were vaccinated as a teenager, you should still take up your screening invitation when you are eligible.

    What if I’ve only ever had one sexual partner?

    You should still attend.

    HPV is extremely common and can be passed through intimate skin-to-skin contact.

    Having had few sexual partners doesn’t mean that your risk is zero.

    And if HPV is detected, it doesn’t tell us when you acquired it or who you acquired it from.

    A positive HPV result is not evidence of infidelity.

    What if I’ve had normal screening results before?

    You should still attend when invited.

    Previous normal results are reassuring, but they don’t mean that you never need screening again.

    Screening works because it is repeated at appropriate intervals.

    It is about identifying risk before cervical cancer develops.

    Symptoms that should be checked

    Whether you have recently had a cervical screening test, regularly attend your appointments, or have had a normal HPV result, you should still speak to your GP or another healthcare professional if you develop new or unusual symptoms.

    These can include:

    • Bleeding between periods
    • Bleeding after sex
    • Bleeding after the menopause
    • Periods that become unusually heavy or different from your normal pattern
    • Unusual or persistent vaginal discharge
    • Pain during sex
    • Persistent pelvic or lower abdominal pain

    There are many different reasons why these symptoms can happen, and having one of them does not mean that you have cervical cancer. Often, there will be a much more straightforward explanation.

    However, it is important not to assume that a recent normal screening result means these symptoms can be ignored.

    Cervical screening looks for high-risk HPV in people who do not have symptoms. If you develop symptoms that are new, persistent or concerning to you, they need to be assessed in their own right.

    So, please don’t wait for your next screening appointment if something doesn’t feel right.

    Know your normal. If something changes and you’re worried about it, get it checked.

    The bottom line

    HPV self-sampling is a really positive development.

    Not because the traditional cervical screening test has suddenly become unnecessary, but because we are recognising that one approach doesn’t work for everyone.

    For some women, being able to take a sample at home may be the thing that finally allows them to take part in screening.

    And if it means reaching women who have repeatedly missed screening, it has the potential to reduce inequalities and prevent more cervical cancers.

    Here in Wales, self-sampling is expected later in 2026, with the initial focus on people who rarely or never attend screening.

    But please don’t wait for it if you already have a cervical screening appointment.

    If you’re invited, please go.

    If you’ve missed an appointment, arrange another one.

    If you’re worried about the examination, tell your healthcare professional.

    And if cervical screening has been something you’ve avoided because the usual process doesn’t work for you, keep an eye out for information from Cervical Screening Wales about the new self-sampling option.

    The important thing isn’t whether you have your screening test at home or in a clinic.

    The important thing is that you have it.

    Because cervical screening isn’t about finding cancer.

    It’s about preventing it.

  • ➡️When Perimenopause Changes More Than Your Periods: Menopause, Autism and ADHD

    “I just don’t feel like myself anymore.”

    Patient’s tell me this often, but for some neurodivergent women, that sentence can mean something particularly significant.

    Perhaps you have noticed that things you have always found difficult suddenly feel almost impossible.

    Your concentration has disappeared. Your tolerance for noise has changed. Social situations that you previously managed now leave you completely exhausted. Your emotions feel harder to regulate. Your routines have become much more important, yet somehow much harder to maintain.

    Perhaps you have ADHD and feel as though your usual strategies for keeping everything together have stopped working.

    Or perhaps you are autistic and find that sensory sensitivities, social demands or changes to your routine have become much harder to cope with.

    It can be very easy to assume that this is simply part of getting older, stress, burnout, ADHD, autism or anxiety.

    Sometimes it is.

    But sometimes there is another piece of the puzzle: perimenopause.

    And I think this is an area of women’s health that deserves much more attention.

    Does menopause affect autistic women differently?

    We are still learning about this.

    The research into menopause and autism is relatively new, but there is now enough evidence to know that we should not simply assume that every woman experiences the menopause transition in the same way.

    A particularly important piece of research has come from Swansea University.

    In 2025, researchers from Swansea University’s School of Health and Social Care published a systematic review looking specifically at autism and the menopause transition. They reviewed eight research studies alongside seven pieces of grey literature.

    The researchers identified three important themes: a lack of knowledge about menopause, experiences of a broad range of menopause symptoms, and inadequate treatment and support. Importantly, they also highlighted that the evidence base remains small and that there are currently no studies properly evaluating specific menopause treatments for autistic people.

    That last point is important.

    We don’t have all the answers yet.

    But we have enough evidence – and enough women telling us about their experiences – to know that this deserves to be taken seriously.

    “Why does everything suddenly feel so much harder?”

    This is perhaps one of the most important questions.

    The symptoms of perimenopause are familiar: changes in periods, hot flushes, night sweats, sleep disturbance, headaches, low mood, anxiety, fatigue and difficulties with concentration and memory.

    But imagine experiencing those changes alongside existing difficulties with sensory processing, executive function, emotional regulation or social interaction.

    The overall effect can be much greater than any individual symptom suggests.

    Research involving autistic women has described experiences such as increased sensory sensitivities, difficulties with emotional regulation, problems coping with everyday demands and a feeling that previously effective coping strategies are no longer working as well.

    The Swansea review found that these difficulties could affect daily activities, work, relationships and mental wellbeing.

    That doesn’t mean that menopause causes these difficulties.

    Rather, the hormonal changes of perimenopause may add another layer of difficulty to things that a woman has already been managing throughout her life.

    When the strategies you’ve always used stop working

    This is something I think is particularly important when we talk about autistic women.

    Many autistic women have spent years developing ways of navigating a world that doesn’t always fit comfortably with the way they experience it.

    They may have developed routines, coping mechanisms and strategies that work extremely well.

    They may also have become very good at masking – consciously or unconsciously adapting their behaviour to fit in socially or to hide difficulties that other people may not see.

    Then perimenopause arrives.

    Sleep becomes worse.

    Concentration becomes harder.

    Your emotional responses may feel more difficult to control.

    Sensory sensitivities may become more intrusive.

    Your ability to cope with noise, social interaction or unexpected changes may decrease.

    And suddenly the strategies that have worked for years don’t seem to be enough.

    That can be incredibly unsettling.

    You may start to wonder:

    “What’s wrong with me?”

    But perhaps the more useful question is:

    “What’s changed?”

    You haven’t necessarily become less capable.

    The demands on your brain and body may simply have changed.

    And what about ADHD?

    There is an interesting overlap here too.

    Many of the symptoms women associate with ADHD – difficulties with concentration, working memory, organisation, motivation, emotional regulation and sleep – can also occur during perimenopause.

    That can make it difficult to work out what is happening.

    Is it your ADHD?

    Is it menopause?

    Is it stress?

    Is it poor sleep?

    Or is it a combination of all of them?

    The answer may be a combination.

    There is growing clinical interest in the relationship between changing oestrogen levels and ADHD symptoms. The British Menopause Society included a dedicated session on “ADHD and autism in the context of managing the menopause” in its 2026 educational programme, specifically addressing oestrogen fluctuations, the brain and ADHD symptoms.

    But it is important not to overstate what we know.

    We cannot currently say that falling oestrogen causes ADHD symptoms, or that HRT is a treatment for ADHD.

    What we can say is that hormonal fluctuations may interact with brain function, and some women with ADHD report that their symptoms become more difficult to manage during the menopause transition.

    That is something worth discussing rather than simply dismissing.

    You may not have “new” symptoms – they may just feel different

    One of the difficulties with recognising menopause in neurodivergent women is that there can be considerable overlap between existing characteristics and menopausal symptoms.

    For example, difficulty concentrating might be attributed to ADHD.

    Poor sleep might be considered part of a long-standing sleep problem.

    Anxiety might be assumed to be unrelated to menopause.

    Feeling overwhelmed might be attributed to autism or stress.

    And fatigue can have almost any explanation.

    This doesn’t mean that every change is menopause.

    It means we need to look at the whole picture.

    If something has changed noticeably around the time your periods begin changing, or you develop other symptoms associated with perimenopause, it is reasonable to consider whether hormonal changes could be contributing.

    At the same time, we shouldn’t put every new symptom into the “menopause” box.

    Thyroid problems, anaemia, medication effects, depression, anxiety and sleep disorders can all cause symptoms that overlap with perimenopause.

    A good menopause consultation should look at the whole person, not just their hormones.

    What does the research tell us about symptoms?

    A 2025 UK study comparing autistic and non-autistic people found that autistic participants reported more bothersome psychological and physical menopause symptoms.

    Interestingly, the researchers did not find a difference in vasomotor symptoms such as hot flushes.

    I think this is an important finding because it reminds us not to create a new stereotype that autistic women necessarily experience every menopause symptom more severely.

    The picture is more complicated than that.

    The differences may be particularly noticeable in areas such as psychological wellbeing, physical symptoms and the ability to manage the changes taking place.

    That fits with what many women describe: it isn’t necessarily one dramatic symptom.

    It is the feeling that everything has become harder to manage at the same time.

    Sometimes the healthcare appointment itself can be difficult

    This is something we need to acknowledge as healthcare professionals.

    If you find certain environments overwhelming, struggle with processing lots of information at once, find unexpected questions difficult or prefer written information, a traditional medical appointment may not always feel particularly accessible.

    And there is evidence that autistic people experience difficulties accessing reproductive and sexual healthcare.

    Research involving autistic adults has highlighted unmet needs around reproductive healthcare, including difficulties discussing reproductive health and menopause and a lack of appropriate accommodation of autistic differences.

    So if you are neurodivergent and find medical appointments difficult, that doesn’t mean you are being difficult.

    It may simply mean that the appointment needs to work differently for you.

    What can make a menopause appointment easier?

    There is no right way to have a medical appointment.

    If it helps, you can:

    • write down your symptoms before you come
    • bring a list of your medications
    • note changes in your periods
    • write down the things that have changed in your ability to cope
    • ask for information to be given to you in writing
    • take someone with you if that helps
    • tell your clinician if you find certain communication styles difficult
    • explain if noise, lighting or busy environments are particularly distracting
    • ask for time to process information before making a treatment decision.

    You don’t have to explain or justify every aspect of being neurodivergent.

    Simply telling your healthcare professional “I process information better if you give me time to think about it” can be enough.

    What about HRT?

    This is where I think we need to avoid two extremes.

    Being autistic or having ADHD does not automatically mean that you need HRT.

    But being neurodivergent should not mean that your menopausal symptoms are dismissed either.

    The usual principles of menopause treatment still apply.

    If you have symptoms that are affecting your quality of life and HRT is medically appropriate for you, it may be one option worth discussing.

    For some women, improving symptoms such as poor sleep, hot flushes, night sweats or other menopausal symptoms may make it easier to manage the other demands of daily life.

    But HRT isn’t a treatment for autism or ADHD.

    It is a treatment for menopausal symptoms, and whether it is appropriate depends on your individual circumstances.

    And if you don’t want HRT, that is also a perfectly reasonable conversation to have.

    There are non-hormonal approaches to managing many menopausal symptoms, as well as lifestyle and practical measures that can make a real difference.

    Lifestyle matters too

    I am always wary of telling women that exercise, eating well and getting enough sleep will somehow solve everything.

    They won’t.

    But they can be an important part of the bigger picture.

    Regular physical activity, good nutrition, maintaining muscle and bone strength, protecting sleep and finding ways to manage stress can all support health during the menopause transition.

    For a neurodivergent woman, I would also think about reducing unnecessary demands.

    Sometimes the most helpful intervention isn’t another supplement or another medication.

    It might be making your environment quieter.

    Changing how you structure your day.

    Building in recovery time after socially demanding activities.

    Protecting your sleep.

    Or accepting that the coping strategies you used in your twenties may need to change in your forties or fifties.

    That isn’t failure.

    It’s adaptation.

    The Swansea research gives us an important message

    I was particularly interested to see this area being researched here in Wales.

    Swansea University researchers are leading participatory work looking at autistic people’s gynaecological and obstetric health across the lifespan, including the transition from menstruation through to menopause. The research involves autistic people in shaping the research itself, which is particularly important when we are trying to understand experiences that have historically received very little attention.

    A 2025 systematic review from the Swansea team also looked specifically at menstruation and autism, highlighting the limited existing evidence and the need for better understanding of autistic people’s reproductive health experiences.

    That matters because we need research that doesn’t simply study neurodivergent women from the outside.

    We need to understand what women themselves are experiencing and what actually helps.

    The research is still developing, but it is encouraging to see this work taking place in Wales and beginning to address an area that has been overlooked for far too long.

    You don’t have to choose between “it’s my autism” and “it’s the menopause”

    Perhaps the most important thing I would say to a woman sitting in front of me is this:

    It doesn’t have to be one or the other.

    You can be autistic and going through perimenopause.

    You can have ADHD and be going through perimenopause.

    You can have both.

    Your neurodivergence doesn’t disappear because you reach menopause, and menopause doesn’t somehow explain away everything you are experiencing.

    But hormonal changes may alter how you experience your existing symptoms and how well your usual coping strategies work.

    Recognising that can be incredibly validating.

    It can also open up more choices.

    The bottom line

    We are still learning about menopause and neurodivergence.

    The research is relatively new, and we need much more of it – particularly research looking at which treatments actually help.

    But that doesn’t mean we should wait for every question to be answered before listening to women.

    If you are autistic or have ADHD and you feel that perimenopause has changed the way you think, sleep, cope, concentrate or experience the world, it is worth talking about.

    You are not imagining it.

    You are not necessarily “just struggling more with your autism”.

    And you are not failing because the strategies that worked for you before don’t seem to be working now.

    Sometimes the menopause transition changes the landscape.

    Our job as healthcare professionals is to recognise that, listen carefully and work with you to find out what is happening – and what might help.

    You deserve menopause care that understands the whole person, not just the symptoms on a checklist.

    REFERENCES

    1. Grant A, Axbey H, Holloway W, et al. (2025). Autism and the Menopause Transition: A Mixed-Methods Systematic Review. Autism in Adulthood. Swansea University researchers reviewed the available evidence on menopause and autism, highlighting the limited evidence base and the need for better understanding and support.
    2. Moseley RL, Druce T, Turner-Cobb JM. (2020). “When my autism broke”: A qualitative study spotlighting autistic voices on menopause. Autism, 24(6), 1423–1437. A UK qualitative study exploring autistic women’s experiences of menopause, including changes in sensory sensitivity, emotional regulation, coping and everyday functioning.
    3. Moseley RL, Druce T, Turner-Cobb JM. (2021). Autism research is “all about the blokes and the kids”: Autistic women breaking the silence on menopause. British Journal of Health Psychology, 26(3), 709–726. A qualitative study exploring awareness, experiences and support needs around menopause among autistic women.
    4. Charlton RA, Happé FG, Shand AJ, Mandy W, Stewart GR. (2025). Self-Reported Psychological, Somatic, and Vasomotor Symptoms at Different Stages of the Menopause for Autistic and Non-autistic People. Journal of Women’s Health, 34(5), 622–634. A UK study comparing reported menopause symptoms in autistic and non-autistic participants.
    5. Grant A, Williams G, Axbey H, et al. (2024). Participatory longitudinal qualitative interview study to understand Autistic gynaecological and obstetric health: the Autism from menstruation to menopause study protocol. BMJ Open, 14, e088343. Swansea University-led research exploring autistic people’s experiences of gynaecological and reproductive healthcare across the lifespan.
    6. British Menopause Society. ADHD and autism in the context of managing the menopause. The BMS has highlighted the emerging clinical evidence and considerations around ADHD, autism and menopause as part of its professional menopause education programme.
    7. National Institute for Health and Care Excellence (NICE). Menopause: identification and management (NG23). NICE guidance on the diagnosis, assessment and management of menopause, including HRT and non-hormonal treatment options.
    8. NHS. Menopause. Patient information covering menopause symptoms, diagnosis and treatment options.

    A NOTE ABOUT THE EVIDENCE

    Research specifically looking at menopause in autistic and ADHD populations is still developing. The evidence base remains relatively small, particularly when it comes to understanding which treatments are most effective for neurodivergent people.

    This means we should be careful not to present emerging findings as established fact. What the research does tell us is that neurodivergent people’s experiences of the menopause deserve to be recognised, listened to and investigated, and that menopause care should be individualised.

  • ➡️Are Painful Periods Normal?

    When period pain may need investigating

    Period pain is common, but severe or disruptive pain shouldn’t always be something you simply learn to live with.

    If you’ve ever said, “My periods are really painful, but I suppose that’s normal”, you’re certainly not alone.

    Over the years, I’ve seen just how easily women can normalise significant period pain.

    It might be because they’ve always had painful periods, because other women in their family experience the same thing, or because they were reassured that painful periods are simply something they have to put up with.

    And while some period pain can be normal, there is a difference between having some discomfort with your period and having pain that regularly interferes with your life.

    So, how do you know which is which?

    Some period pain is normal

    Period pain, or dysmenorrhoea, is very common. It usually happens around the beginning of your period and is caused by the uterus contracting as it sheds its lining.

    You might experience some cramping or aching in your lower abdomen, perhaps with some backache or a general feeling of discomfort.

    For many women, this is manageable with simple measures such as heat, rest and appropriate pain relief, and it settles within the first few days of the period.

    But period pain shouldn’t have to take over your life.

    If you regularly find yourself arranging your work, social life, exercise or family commitments around your period because you know you’ll be in too much pain to function normally, that’s something I’d want to hear about.

    “But my periods have always been like this…”

    This is one of the most common things I hear in clinic.

    And I completely understand why women assume that long-standing symptoms must be normal.

    You may have grown up hearing that periods are painful. Perhaps your mum had terrible periods too. Maybe you’ve always been told that it’s simply part of being a woman.

    But just because something is common doesn’t mean you have to put up with it.

    Pain that has been there for years can still have a cause, and sometimes women don’t realise how much their symptoms have affected their lives until they start talking about them properly.

    What sort of period pain should you have checked?

    I would encourage you to speak to a healthcare professional if your period pain:

    • Is severe or regularly stops you from doing normal activities.
    • Makes you miss work, school, exercise or social plans.
    • Requires you to take regular or strong pain relief just to get through your period.
    • Is getting worse over time.
    • Lasts for several days or continues after your period has finished.
    • Is associated with pain during or after sex.
    • Causes pain when opening your bowels or passing urine, particularly around your period.
    • Is accompanied by persistent pelvic pain between periods.
    • Is affecting your fertility or you are having difficulty conceiving.

    You don’t need to have all of these symptoms. If your pain is affecting your quality of life, it’s reasonable to ask whether there might be an underlying reason.

    Could there be a reason for your pain?

    There are several conditions that can cause painful periods or pelvic pain.

    Endometriosis

    Endometriosis is one of the conditions we think about when period pain is severe, particularly when there are other symptoms such as pain during sex, bowel or bladder symptoms, or difficulties with fertility.

    Importantly, endometriosis doesn’t look the same in every woman.

    Adenomyosis

    Adenomyosis occurs when tissue similar to the lining of the womb grows into the muscle of the uterus.

    It can cause painful periods, heavy bleeding and pelvic pain, and symptoms can sometimes become more noticeable as women get older.

    Fibroids

    Fibroids are non-cancerous growths that develop in or around the womb. Depending on their size and location, they can cause heavier periods, pelvic pressure or pain.

    Other causes

    There are other possible causes of pelvic or period pain too, including ovarian cysts, pelvic infections and other gynaecological conditions.

    That’s why the symptoms you describe are just as important as what we see on a scan.

    What if my ultrasound is normal?

    This is another really important question.

    A normal ultrasound scan can be reassuring, but it doesn’t necessarily mean that there is no explanation for your symptoms.

    Some conditions can be difficult to identify, particularly if the scan isn’t performed with a specific clinical question in mind. This is why, when we’re investigating pelvic pain, we don’t just look at the scan in isolation.

    Your symptoms, your menstrual cycle, your medical history, any previous surgery or pregnancies, your fertility plans and what you’re experiencing day to day all help us understand the bigger picture.

    A good gynaecological assessment isn’t simply about looking at an ultrasound image and saying, “Everything looks normal.”

    It’s about asking whether the findings make sense alongside your symptoms.

    So, what should you do if your periods are really painful?

    The first step is simply to talk to someone.

    Try to be as specific as you can about what your pain is like and how it affects you. It can be helpful to keep a note of when the pain happens in relation to your period, how severe it is, how long it lasts and whether you notice other symptoms.

    You don’t need to arrive at an appointment knowing whether you have endometriosis, adenomyosis or something else. You just need to be able to tell us what you’re experiencing.

    From there, we can decide whether further assessment or investigation would be helpful.

    You don’t have to put your life on hold for your periods

    One of the things I would most like women to take away from this is that painful periods are common, but debilitating period pain isn’t something you should automatically accept as your normal.

    You know your body better than anyone.

    If your period regularly leaves you curled up in bed, unable to work, unable to exercise, unable to sleep, or planning your life around when your next period is due, it’s worth talking about.

    There may be a straightforward explanation. There may be something that needs further investigation. And sometimes we may not find a single cause straight away.

    But you deserve to be listened to.

    If your periods are affecting your life, don’t be afraid to ask: “Is this really normal for me?”

    It may be the first step towards getting the answers you’ve been looking for.

  • ➡️ Why Does My Gynaecologist Keep Suggesting Contraception?

    A patient comes to see me because her periods are painful, heavy or unpredictable. Perhaps she has endometriosis, adenomyosis or PCOS. Perhaps she has been struggling with pelvic pain or debilitating periods for years.

    And then I mention the pill, the hormonal coil or another hormonal treatment.

    The response is sometimes immediate:

    “But I’m not looking for contraception.”

    And I completely understand why.

    If you have come to a gynaecology appointment looking for an explanation or treatment for your symptoms, being offered contraception can sometimes feel like you are being fobbed off.

    So why do gynaecologists seem to suggest contraception so often?

    The answer is that we are not always thinking about contraception.

    Sometimes we are thinking about hormones.

    Contraception can be a treatment – even when you don’t need contraception

    This is probably the most important distinction to make.

    Some of the medications we call “contraceptives” have effects that can be very useful in treating gynaecological conditions.

    For example, hormonal contraception can change the way you experience your periods. Depending on the method, it can make periods lighter, less painful, less frequent or stop them altogether.

    That can be particularly helpful for women with conditions such as endometriosis, adenomyosis or heavy menstrual bleeding. Hormonal treatment is one of the options recommended for managing pain associated with endometriosis, for example.

    So when I suggest the pill or a hormonal coil to a woman who isn’t trying to prevent pregnancy, I am not necessarily thinking:

    “She needs contraception.”

    I may instead be thinking:

    “Can we reduce the hormonal stimulation and menstrual bleeding that is contributing to her symptoms?”

    Those are two quite different conversations.

    So why hormones?

    The menstrual cycle is a hormonal process.

    Every month, your ovaries produce hormones that cause the lining of the womb to grow and then shed when you have your period.

    For some women, that cycle is associated with significant pain or bleeding. In conditions such as endometriosis and adenomyosis, hormonal activity can be closely linked to symptoms.

    One way of treating those symptoms is therefore to alter what the hormones are doing.

    Depending on the treatment, we might:

    • reduce or stop ovulation
    • make the womb lining thinner
    • reduce menstrual bleeding
    • make periods less frequent
    • stop periods altogether
    • reduce the hormonal stimulation associated with endometriosis
    • reduce the cyclical nature of pelvic pain.

    That is why something that was originally developed or is commonly used as contraception can also have a place in gynaecological treatment.

    The contraceptive effect may simply be an additional effect that isn’t relevant to you.

    “But I don’t want to take hormones.”

    This is another conversation I have regularly – and I think it is an important one.

    Some women are understandably reluctant to take hormones.

    Perhaps you have had unpleasant side effects in the past. Perhaps you didn’t feel like yourself on the pill. Maybe you are worried about mood changes, weight gain, libido or other side effects. Or perhaps you simply don’t like the idea of taking hormones when you don’t feel that your body needs them.

    Those concerns are valid.

    And “I don’t want hormones” is not something that should simply be brushed aside.

    Hormonal treatments are medicines, and like all medicines they can have benefits, side effects and risks. Different hormonal methods contain different hormones, in different doses and delivered in different ways, so your experience of one method does not necessarily tell us exactly how you will respond to another.

    The conversation shouldn’t be:

    “You have this condition, therefore you need hormones.”

    It should be:

    “These are the options available to us. This is why I think this treatment might help. How do you feel about it?”

    That distinction matters.

    Are we actually treating the condition – or just masking the symptoms?

    This is probably one of the biggest concerns women have.

    If the pill makes your periods less painful, does that mean the underlying problem has gone away?

    Not necessarily.

    Hormonal treatment can be very effective at controlling symptoms, but symptom control and treating the underlying cause are not always the same thing.

    For some women, controlling symptoms may be exactly what they need. For others, we may need to investigate further, consider imaging, look for conditions such as fibroids, adenomyosis or endometriosis, or discuss other treatment options.

    This is why I would never want a woman to feel that being offered hormonal treatment means that we are simply trying to make her symptoms disappear without finding out what is causing them.

    Sometimes hormonal treatment is part of the answer.

    Sometimes it isn’t.

    And sometimes it is one step in a much bigger treatment plan.

    What if I don’t want contraception or hormones?

    This is where the conversation becomes particularly important.

    There isn’t one treatment that is right for every woman.

    For example, if you have heavy periods and don’t want hormonal treatment, there are non-hormonal options such as tranexamic acid or anti-inflammatory medication that may be appropriate, depending on your circumstances and the underlying cause.

    The right treatment also depends on what you are trying to achieve.

    Are you:

    • trying to become pregnant?
    • hoping to avoid pregnancy?
    • wanting to keep your natural menstrual cycle?
    • struggling with heavy bleeding?
    • dealing with severe period pain?
    • experiencing pain throughout the month?
    • concerned about the effect of hormones on your mood or wellbeing?
    • hoping to avoid medication altogether?

    These are all important parts of the conversation.

    And if you are actively trying to conceive, that obviously changes the treatment options considerably.

    What are the non-hormonal options?

    If you don’t want to use hormones, that doesn’t mean you are left without treatment.

    The options will depend very much on what is causing your symptoms, but non-hormonal treatments can be useful for many women.

    For heavy periods, for example, medicines such as tranexamic acid can reduce menstrual blood loss, while anti-inflammatory medicines such as ibuprofen or mefenamic acid can help with both pain and bleeding for some women.

    There is also much more to managing gynaecological symptoms than medication alone. Depending on your symptoms and diagnosis, lifestyle measures such as regular physical activity, sleep, nutrition, managing stress and maintaining a healthy weight can all form part of a broader approach to looking after your health and managing symptoms.

    For conditions such as endometriosis, adenomyosis or fibroids, treatment needs to be individualised. This might involve medication, non-hormonal approaches, lifestyle and supportive measures, monitoring, further investigation or, in some circumstances, a procedure or surgery. Sometimes a combination of approaches works best.

    The important thing is that treatment should fit the problem – but it should also fit you.

    If you don’t want hormones, tell your gynaecologist. It is a useful starting point for the conversation, not the end of it.

    “I feel like I’m being fobbed off with the pill.”

    If you’ve heard this before, you’re not alone.

    I think sometimes the frustration comes from the fact that women have been told for years that the answer to period problems is simply “try the pill”.

    If you’ve been having severe pain for years, you may quite reasonably think:

    “Surely there must be more to it than that?”

    And sometimes there is.

    A hormonal treatment may be a perfectly reasonable treatment for your symptoms, but that doesn’t mean that your symptoms shouldn’t also be properly assessed.

    Heavy or painful periods can have many causes, including endometriosis, adenomyosis and fibroids. The impact on your quality of life is also important.

    So if you’ve been offered contraception and you’re wondering why, ask.

    “What are we hoping this treatment will do for my symptoms?”

    “Are you suggesting this because I need contraception, or because of the hormonal effect?”

    “What are my non-hormonal options?”

    “Do we know what is causing my symptoms?”

    “What happens if I don’t want to take this?”

    These are all completely reasonable questions.

    And what about the word “hormones”?

    I think we can sometimes forget just how emotionally loaded that word has become.

    We talk about “taking hormones” as though it is one single thing.

    But hormonal medicines are not all the same.

    The combined pill contains oestrogen and a progestogen. Some treatments contain progestogen alone. A hormonal coil releases a progestogen within the womb. Other treatments used in gynaecology can work on the hormonal system in very different ways.

    So if you’ve previously had a bad experience with one hormonal treatment, tell your doctor.

    It doesn’t necessarily mean that every hormonal option will affect you in exactly the same way.

    But equally, if you don’t want hormonal treatment, that is important information too.

    Sometimes doing less is a perfectly reasonable choice

    Not every symptom has to be treated with medication.

    Sometimes symptoms are manageable and you may decide that you don’t want treatment at all.

    Sometimes you may prefer to monitor things.

    Sometimes you may want to investigate further before deciding on treatment.

    And sometimes you may want to try a non-hormonal approach first.

    As a gynaecologist, my job isn’t simply to find something I can prescribe.

    It is to understand what is happening, explain the options and help you decide what feels right for you.

    The bottom line

    So, why do gynaecologists seem to recommend contraception so often?

    Because some contraceptive methods are also very effective gynaecological treatments.

    They can reduce bleeding, make periods less painful, suppress ovulation and alter the hormonal environment that contributes to certain conditions.

    But that doesn’t mean contraception is the only answer.

    And it certainly doesn’t mean you should feel pressured into taking hormones that you don’t want.

    If a hormonal treatment is suggested, it is completely reasonable to ask why it has been recommended specifically for you, what it is expected to achieve, what the alternatives are and whether there are non-hormonal options.

    If you feel that you are being offered the pill simply because your doctor doesn’t know what else to do, say so.

    And if you don’t want hormones, say that too.

    The best gynaecology consultations aren’t about persuading you to take a particular treatment.

    They’re about understanding what is happening, explaining the choices and finding a treatment plan that makes sense for you.

  • ➡️ Why Iron Deficiency Is So Common in Women – And Why It Shouldn’t Be Ignored

    “I’m exhausted all the time.”

    It is something I hear regularly from women in clinic. Sometimes it is put down to a busy life, poor sleep, stress, work or simply having too much going on.

    And sometimes those things are contributing.

    But persistent tiredness, low energy or feeling unusually breathless can also be signs that your iron levels are low.

    Iron deficiency is extremely common, particularly in women, and one of the things I think is important is not to simply accept symptoms such as fatigue as something you have to put up with. There is often a reason why your iron levels have fallen, and finding that reason is an important part of treatment.

    Why do we need iron?

    Iron is essential for making haemoglobin, the protein in our red blood cells that carries oxygen around the body.

    When your iron stores become low, your body has less available iron to make healthy red blood cells. If the deficiency becomes significant, this can eventually lead to iron deficiency anaemia.

    But importantly, you do not necessarily have to be anaemic to feel the effects of low iron.

    Iron stores can become depleted before your haemoglobin falls outside the normal range, which means some women can experience symptoms even though they have been told that their blood count is “normal”.

    Why is iron deficiency so common in women?

    There are several reasons, but in my experience, one of the first things worth considering is menstrual blood loss.

    Heavy periods

    Every month that you have a period, you lose some blood – and therefore some iron.

    If your periods are particularly heavy or prolonged, those losses can gradually add up. Over time, your body’s iron stores can become depleted.

    Heavy menstrual bleeding can be associated with conditions such as:

    • fibroids
    • adenomyosis
    • endometriosis
    • hormonal changes
    • some types of contraception.

    One thing I would really encourage women not to do is assume that heavy periods are simply something they have to live with.

    If your periods are affecting your energy, your ability to work, exercise or enjoy everyday life, they are worth discussing. Heavy bleeding can affect much more than just your menstrual cycle.

    Pregnancy

    Pregnancy places considerably greater demands on your body’s iron stores.

    You need additional iron to support your growing baby and placenta, as well as the increase in your own blood volume.

    If your iron stores were already low before pregnancy, they can become depleted more quickly.

    This is one reason why iron levels are an important part of looking after your health during pregnancy and when planning a family.

    Diet

    Diet can also play a role.

    There are plenty of good sources of iron in both animal-based and plant-based diets. These include:

    • red meat
    • poultry
    • fish and seafood
    • eggs
    • beans and lentils
    • chickpeas
    • tofu and other soya products
    • dark green leafy vegetables such as spinach
    • nuts and seeds
    • wholegrains
    • iron-fortified breakfast cereals.

    If you are vegetarian or vegan, you can absolutely get enough iron from a well-planned diet. However, the type of iron found in plant foods is absorbed differently from the iron found in meat and fish, so paying attention to the combination of foods you eat can be helpful.

    Vitamin C can improve the absorption of iron from plant foods, so try combining iron-rich foods such as beans, lentils, tofu or leafy greens with foods such as peppers, tomatoes, citrus fruits, berries or broccoli.

    There are also some foods and drinks that can reduce iron absorption when consumed around the same time as an iron-rich meal, including tea and coffee.

    If you follow a vegetarian or vegan diet and are concerned about your iron levels, it does not automatically mean that your diet is inadequate. It may simply be worth reviewing what you are eating and, if you have symptoms or a history of iron deficiency, checking your iron levels.

    Sometimes it isn’t your diet or your periods

    Iron deficiency isn’t always explained by menstrual blood loss or diet.

    Conditions affecting the digestive system, including coeliac disease and inflammatory bowel disease, can affect how well your body absorbs iron. Other gastrointestinal conditions can also cause blood loss.

    If iron deficiency keeps coming back despite treatment, it is particularly important to look at why.

    Sometimes iron deficiency is the first clue that something else needs investigating.

    What does iron deficiency actually feel like?

    Iron deficiency can develop gradually, which makes it surprisingly easy to overlook.

    You might notice:

    • feeling tired or lacking energy
    • becoming more breathless than usual
    • dizziness or light-headedness
    • headaches
    • difficulty concentrating or “brain fog”
    • looking paler than usual
    • heart palpitations
    • brittle nails
    • hair thinning or increased hair shedding
    • restless legs, particularly at night.

    These symptoms can have many possible causes. Women may understandably attribute them to stress, poor sleep, menopause, a busy lifestyle or simply getting older.

    But if something doesn’t feel right, it is worth investigating rather than assuming you just need to slow down or get more sleep.

    Can you be iron deficient without being anaemic?

    Yes – and this is an important distinction.

    Iron deficiency and iron deficiency anaemia are not exactly the same thing.

    Your body’s iron stores, which can be assessed using a blood test called ferritin, can become depleted before your haemoglobin falls enough to meet the criteria for anaemia.

    This means you may have symptoms associated with low iron even if your full blood count has been described as “normal”.

    If iron deficiency is suspected, your clinician may therefore look at more than just your haemoglobin.

    How do we check your iron levels?

    Iron deficiency is usually investigated with blood tests.

    Depending on your symptoms and circumstances, your clinician may request:

    • a full blood count (FBC)
    • ferritin, which gives an indication of your body’s iron stores
    • additional iron studies where appropriate.

    The blood test is important, but so is understanding why your iron levels are low.

    If you have heavy periods, for example, simply replacing the iron without addressing the heavy bleeding may mean the problem keeps coming back.

    How is iron deficiency treated?

    Treatment depends on the cause and how significant the deficiency is.

    It may involve:

    • improving dietary iron intake
    • oral iron supplements
    • intravenous (IV) iron in selected circumstances
    • treating heavy menstrual bleeding
    • investigating and treating an underlying medical condition.

    Some women begin to feel more energetic within a few weeks of treatment, but restoring your body’s iron stores can take considerably longer.

    It is therefore important to follow the treatment plan recommended for you rather than stopping treatment as soon as you start to feel better.

    When should you speak to someone?

    I’d recommend speaking to a healthcare professional if you are experiencing:

    • persistent or unexplained tiredness
    • heavy or prolonged periods
    • increasing breathlessness
    • dizziness or light-headedness
    • recurrent iron deficiency
    • hair loss or significant hair shedding
    • symptoms that are beginning to interfere with your everyday life.

    And particularly if you have been treated for iron deficiency before and it keeps returning, it is worth asking whether there may be an underlying reason.

    The bottom line

    Iron deficiency is common in women, but that doesn’t mean it should be considered normal.

    For women with heavy periods, the monthly loss of blood can gradually deplete iron stores without it necessarily being obvious at first. Pregnancy, dietary intake and conditions affecting absorption or causing blood loss can also play a role.

    The good news is that iron deficiency is usually straightforward to investigate with blood tests, and there are effective treatments available.

    If you’re constantly tired, struggling with your energy or finding that your periods are particularly heavy, don’t simply assume it is part of being busy or part of getting older.

    Sometimes a simple blood test can provide an important piece of the puzzle – but the real goal is not just to replace the iron. It is to understand why you became deficient in the first place.

  • ➡️ GLP-1 Medications and Women’s Health: What Every Woman Should Know

    Over the last few years, medications such as Mounjaro® (tirzepatide), Wegovy® (semaglutide) and Ozempic® (semaglutide) have become increasingly familiar. They can be very effective treatments for obesity and type 2 diabetes, and I am now seeing more and more women asking about how these medications might affect their hormones, periods, fertility and reproductive health.

    There is a lot of information – and misinformation – online, so it is understandable that women have questions.

    One of the things I often discuss with patients is that GLP-1 medications are not simply about weight loss. For some women, the changes that happen as a result of treatment can have wider effects on their menstrual cycle, ovulation and fertility. If pregnancy is something you are considering, there are also some important things to know before starting treatment.

    So, what exactly are GLP-1 medications?

    GLP-1 receptor agonists, along with medications such as tirzepatide which act on both GIP and GLP-1 receptors, work in several ways to help regulate appetite and blood sugar.

    They can:

    • reduce appetite and food intake
    • help you feel fuller for longer
    • slow the rate at which food leaves the stomach
    • improve blood sugar control
    • support significant weight loss when combined with appropriate lifestyle changes.

    For many women, these changes can have meaningful benefits for their overall health. But it is also worth considering what they might mean specifically for women’s hormonal and reproductive health.

    Could GLP-1 medication change your periods?

    This is something women sometimes notice after starting treatment.

    Some women report that their periods become more regular, while others notice a change in their cycle length or bleeding pattern. For women who have previously had irregular periods, particularly those with PCOS, weight loss can sometimes be accompanied by the return of more regular ovulation.

    It is important, however, not to assume that the medication itself is directly changing your menstrual cycle.

    Weight, insulin resistance and hormonal balance are all closely linked to menstrual health. As these change, particularly with weight loss, your periods and ovulation may change too.

    So, if your cycle changes after starting a GLP-1 medication, it is worth discussing this with your healthcare professional rather than simply assuming it is a side effect.

    What about GLP-1 medications and PCOS?

    This is an area I am asked about increasingly in clinic.

    Women with PCOS can experience insulin resistance, irregular periods and difficulties with ovulation, and weight can be one factor contributing to these problems.

    For women who are overweight or living with obesity, losing weight can sometimes improve:

    • insulin resistance
    • ovulation
    • menstrual regularity
    • blood pressure
    • cholesterol
    • overall metabolic health.

    There is growing interest in the potential role of GLP-1 medications in women with PCOS, and some studies have reported improvements in ovulation and fertility-related hormones alongside weight loss.

    However, GLP-1 medications are not currently licensed specifically as a treatment for PCOS. Whether they are appropriate depends on the individual woman, her symptoms, her health and what she is hoping to achieve.

    Could you actually become more fertile?

    This is one of the most important things to be aware of.

    A woman who has had irregular or infrequent ovulation may find that ovulation becomes more regular following weight loss. This can be a very positive change – but it also means that pregnancy can become possible, sometimes unexpectedly.

    I have seen how easy it is for women to think that because their periods have always been irregular, or because they have previously struggled to conceive, pregnancy is unlikely.

    That is not necessarily the case.

    If you do not want to become pregnant, it is important to make sure you have reliable contraception in place and to discuss this with the healthcare professional prescribing your medication.

    What do GLP-1 medications mean for contraception?

    This is particularly important if you are taking tirzepatide (Mounjaro®).

    Because tirzepatide can slow stomach emptying, it may affect the absorption of the oral contraceptive pill, particularly when you first start treatment or after your dose is increased.

    Current UK guidance recommends using a barrier method, such as condoms, for four weeks after starting tirzepatide and for four weeks after each dose increase. Alternatively, you may wish to consider a non-oral method of contraception.

    This additional precaution does not currently apply in the same way to semaglutide, but contraception is still something worth discussing with your clinician, particularly if your periods or ovulation are changing.

    What if you are thinking about having a baby?

    This is a conversation I would always encourage women to have before starting a GLP-1 medication if pregnancy is something they may want in the future.

    GLP-1 medications are not recommended during pregnancy, and they should be stopped sufficiently in advance of trying to conceive.

    Current recommendations advise stopping:

    • Semaglutide (Ozempic® or Wegovy®): at least two months before trying to become pregnant
    • Tirzepatide (Mounjaro®): at least one month before trying to become pregnant

    If you become pregnant while taking a GLP-1 medication, don’t panic, but do contact your healthcare professional promptly so that you can receive appropriate advice.

    What about breastfeeding?

    This is another area where we don’t yet have all the answers.

    There is currently limited evidence about the safety of GLP-1 medications during breastfeeding, so they are generally not recommended while breastfeeding unless specifically advised by a specialist.

    Are side effects common?

    As with any medication, GLP-1 treatments can cause side effects.

    The ones women most commonly notice include:

    • nausea
    • vomiting
    • diarrhoea
    • constipation
    • abdominal discomfort.

    For many people these symptoms settle as the body gets used to the medication, particularly when treatment is introduced gradually.

    Less commonly, more significant problems such as gallstones, pancreatitis or dehydration can occur. If you experience severe abdominal pain or persistent vomiting, you should seek medical advice.

    Are GLP-1 medications right for you?

    There is no simple yes or no answer to this.

    These medications can be extremely helpful for the right patient, but they are not suitable for everyone. I would always recommend looking at the bigger picture rather than simply focusing on the number on the scales.

    When considering treatment, we need to think about things such as your:

    • general health
    • BMI and weight-related health risks
    • existing medical conditions
    • other medications
    • menstrual and reproductive health
    • plans for pregnancy
    • individual goals and preferences.

    For women, in particular, I think it is important that conversations about GLP-1 medications go beyond weight and metabolic health.

    Your periods, contraception, fertility and plans for pregnancy all form part of the picture.

    The bottom line

    GLP-1 medications have changed the way we approach obesity and type 2 diabetes, and for many people they can be incredibly beneficial.

    For women, however, there are some additional considerations that are easy to overlook.

    If your weight changes, your periods or ovulation may change too. If you have PCOS, this may sometimes mean more regular ovulation – and potentially increased fertility. If pregnancy isn’t planned, contraception becomes particularly important. And if you are thinking about starting a family, the timing of stopping your medication needs to be considered carefully.

    My advice is not to be frightened of these medications, but to make sure you understand how they fit into your own health and reproductive plans.

    If you are considering a GLP-1 medication and have questions about your periods, PCOS, fertility, contraception or plans for pregnancy, speak to your healthcare professional. A personalised conversation is much more useful than trying to work out what applies to you from something you have read online.

    As we use these medications more widely, we are also learning more about their potential role in women’s health. It is an area that I expect will continue to develop over the coming years.

  • ➡️ Introducing WID-easy® to Wales – Innovation with a Purpose

    Women’s healthcare is changing.

    Across Wales there is a growing recognition that women deserve to be listened to, investigated promptly and given access to the very best evidence-based care. The Welsh Government’s Women’s Health Plan has placed women’s health firmly on the national agenda, recognising the importance of earlier diagnosis, reducing inequalities and bringing specialist care closer to where women live.

    At West Wales Women’s Wellbeing, we couldn’t agree more.

    We believe every woman deserves to feel listened to, understood and reassured.

    When a woman comes to see us with abnormal bleeding, she is often carrying much more than a symptom. She may be anxious about what it means, frustrated by months of uncertainty or simply hoping for clear answers. Our role is not only to investigate those symptoms but to provide expert care with kindness, compassion and reassurance every step of the way.

    That philosophy guides everything we do.

    We are continually looking for ways to improve the care we provide. Sometimes that means embracing exciting new innovations. At other times, it means introducing well-established diagnostic techniques that are already supported by evidence but are not yet widely available in routine clinical practice. Whatever the innovation, our guiding question is always the same:

    “Will this genuinely improve the care and experience of our patients?”

    If the answer is yes, we want women in West Wales to benefit from it.

    That is why we were proud to become the first independent women’s health service in Wales to introduce the WID-easy® endometrial cancer test into routine clinical practice. Since introducing the test, we have incorporated it into our comprehensive assessment pathway for women with abnormal uterine bleeding and have gained increasing experience and confidence in its use alongside specialist ultrasound.

    Looking Beyond a Single Test

    Abnormal uterine bleeding is one of the commonest reasons women are referred to a gynaecologist. While the vast majority of women do not have endometrial cancer, one of our most important responsibilities is identifying those who do, while providing reassurance to the many who do not.

    Historically, many women have undergone hysteroscopy and endometrial biopsy to investigate abnormal bleeding. These remain extremely valuable investigations and continue to play an important role in diagnosing pathology within the uterus.

    However, not every woman needs an invasive procedure.

    Modern diagnostics now allow us to take a more personalised approach by combining different investigations to build a clearer understanding of what is happening before deciding on the next step.

    Combining the Best Diagnostic Tools

    At West Wales Women’s Wellbeing, we believe that no single investigation provides every answer.

    Instead, we combine expert clinical assessment with specialist transvaginal ultrasound, Saline Infusion Sonography (SIS) and, where appropriate, WID-easy®.

    Specialist ultrasound provides a detailed assessment of the uterus, ovaries and pelvis. Saline Infusion Sonography allows us to examine the uterine cavity in much greater detail, identifying polyps, submucosal fibroids and other structural abnormalities that may not be visible on ultrasound alone.

    Alongside this, WID-easy® provides additional information about the likelihood of endometrial cancer using molecular diagnostic technology.

    Together, these investigations provide a far more complete picture than any single test could achieve on its own.

    Reducing Unnecessary Procedures

    One of the greatest advances in modern medicine is not simply performing more investigations—it is ensuring that each investigation is appropriate for the individual woman.

    When specialist ultrasound, SIS and WID-easy® all provide reassuring findings, many women can be managed confidently without proceeding immediately to hysteroscopy. This can reduce unnecessary invasive procedures, minimise anxiety and provide reassurance much sooner.

    Where imaging identifies abnormalities within the uterine cavity, where WID-easy® raises concern, or where the overall clinical picture indicates that further assessment is needed, hysteroscopy can then be directed towards the women who are most likely to benefit.

    Our aim is simple: to ensure every woman receives the right investigation, at the right time, for the right reason.

    Supporting the Future of Women’s Healthcare in Wales

    The direction of women’s healthcare in Wales is increasingly focused on delivering more specialist care within communities, improving access and embracing innovation. New Women’s Health Hubs are now being established across every health board, reflecting a shared ambition to provide timely, expert care closer to home.

    We see our work as complementing this wider vision.

    As an independent specialist service, we are able to evaluate emerging evidence, introduce validated diagnostic technologies and integrate them into comprehensive, consultant-led care pathways. Our goal is not simply to offer new tests, but to ensure that every innovation is used thoughtfully, responsibly and in a way that genuinely benefits women.

    National media have also highlighted the potential of WID-easy® to reduce unnecessary invasive investigations while providing faster reassurance for many women experiencing abnormal bleeding.

    Looking Ahead

    Introducing WID-easy® to Wales was one step on our journey, not the destination.

    As women’s healthcare continues to evolve, so will we.

    We will continue to seek out innovations that are supported by good evidence, carefully evaluate new technologies and introduce those that genuinely improve patient care. Whether that is a pioneering diagnostic test, advances in ultrasound or new approaches to outpatient investigation, our commitment remains the same: to provide the highest standards of specialist women’s healthcare as close to home as possible.

    Above all, we hope every woman who walks through our doors leaves feeling something that matters just as much as the diagnosis itself—that she has been listened to, cared for, respected and given clear answers with kindness, expertise and compassion.

    Because great women’s healthcare is about much more than diagnosing a condition.

    It is about giving women confidence, reassurance and the knowledge that they have received the very best care at a time when they needed it most.


    Further Reading

    If you would like to learn more about the future of women’s healthcare in Wales and the innovations shaping modern gynaecology, these resources provide an excellent overview:

  • ➡️ Women’s Health in Wales: A New Era of Community Care

    For generations, women have often accepted that long waits, repeated appointments and delayed diagnoses are simply part of healthcare. Whether living with heavy periods, pelvic pain, endometriosis, menopause symptoms, fertility concerns or abnormal bleeding, too many women have experienced unnecessary delays before receiving the answers they deserve.

    Thankfully, this is beginning to change.

    Across Wales there is growing recognition that investing in women’s health is not only the right thing to do for women and their families, it is also essential for the future sustainability of our healthcare system. Earlier diagnosis, better access to specialist assessment and modern diagnostic techniques can improve quality of life, reduce unnecessary hospital referrals and ensure that women receive the right treatment at the right time.

    The Importance of Early Diagnosis

    Many gynaecological conditions develop gradually. Symptoms such as heavy menstrual bleeding, pelvic pain, bloating, irregular bleeding or menopause-related concerns are often initially dismissed or normalised. Yet these symptoms may represent conditions such as fibroids, endometriosis, adenomyosis, ovarian cysts or abnormalities within the womb.

    The earlier these conditions are identified, the greater the opportunity to:

    • Prevent symptoms becoming more severe.
    • Avoid unnecessary emergency presentations.
    • Offer less invasive treatments.
    • Support fertility where appropriate.
    • Improve long-term physical and emotional wellbeing.
    • Reduce the need for major surgery.

    Modern women’s healthcare is increasingly centred around making an accurate diagnosis first, allowing treatment to be tailored to each individual woman rather than following a one-size-fits-all approach.

    Bringing Specialist Care Closer to Home

    One of the greatest challenges facing rural Wales has always been access.

    Women should not have to travel long distances or wait many months simply to receive an expert assessment. Community-based specialist services can help bridge that gap by delivering high-quality diagnostics closer to where women live.

    Consultant-led ultrasound, advanced outpatient investigations and comprehensive women’s health assessment can often provide answers in a single visit, reducing uncertainty and helping women move more quickly towards appropriate treatment.

    This model not only improves patient experience but also helps relieve pressure on busy hospital services.

    The Role of Modern Diagnostics

    Advances in ultrasound and outpatient diagnostics are transforming the way gynaecological conditions are investigated.

    Many procedures that previously required admission to hospital can now be performed safely and comfortably in an outpatient setting.

    Modern investigations can assess:

    • The uterus and endometrium.
    • Ovarian health.
    • Fibroids and adenomyosis.
    • Fallopian tube patency.
    • Uterine cavity abnormalities.
    • Early pregnancy concerns.
    • Fertility assessment.
    • Menopause-related bleeding.

    Accurate imaging allows clinicians to make informed decisions, avoid unnecessary procedures where possible and ensure women receive the most appropriate care based on evidence rather than uncertainty.

    Expert Care Matters

    Technology is only one part of the equation.

    Perhaps even more important is ensuring that women are assessed by clinicians with specialist expertise in women’s health. Experience matters when interpreting symptoms, performing advanced ultrasound and guiding treatment decisions.

    Every woman deserves time to be listened to, for her concerns to be taken seriously and for investigations to be explained clearly. A diagnosis is only valuable when it is accompanied by compassionate, personalised care.

    Looking Ahead

    The future of women’s healthcare in Wales is exciting. The Welsh Government’s Women’s Health Plan recognises the importance of improving access, reducing inequalities and ensuring women receive timely, high-quality care throughout every stage of life.

    At the heart of this transformation is innovation—not innovation for its own sake, but the thoughtful adoption of new evidence, new technologies and new ways of delivering care. Some advances are entirely new, while others are well-established internationally but have yet to become widely available in routine clinical practice. Bringing these innovations closer to home has the potential to improve the patient experience, provide earlier answers and support more personalised care.

    Our Vision

    At West Wales Women’s Wellbeing, we are committed to continually developing the services we offer. We actively seek out evidence-based innovations that have the potential to benefit women across West Wales, carefully evaluating new technologies and introducing established diagnostic tests where they can add genuine clinical value.

    Examples include advanced outpatient investigations such as saline infusion sonography (SIS), Hysterosalpingo-Foam Sonography (HyFoSe) for fertility assessment, and emerging technologies such as the WID-easy® endometrial cancer test, alongside high-quality specialist ultrasound. Our aim is always to complement existing healthcare pathways by offering women access to modern diagnostics delivered safely, compassionately and as close to home as possible.

    Healthcare continues to evolve, and so do we. By embracing innovation responsibly and working alongside established services, we hope to play our part in shaping a future where women have faster access to expert assessment, earlier diagnosis and more informed choices about their care.

    Every woman deserves to be heard. Every woman deserves timely answers. And every woman deserves access to expert, evidence-based care, wherever she lives.