We’ve been asked by a number of women what we make of the news about HPV self-sampling, particularly those living here in Wales, so we thought it would be helpful to explain what’s actually happening, what the evidence tells us, and what it means for you.
You may have seen the news that women in England are now being offered the option of doing an HPV test at home.
For some women, this will be very welcome news.
The thought of making an appointment, having a speculum examination and having a sample taken from the cervix can be a significant barrier to cervical screening. For some, it may be anxiety and uncertain. For others, it may be a previous experience or trauma. There can also be very practical barriers – finding an appointment, taking time off work, arranging childcare or simply finding the time to attend.
So the idea of being able to take your own sample at home sounds very appealing.
But if you live in Wales, there is an important distinction to make.
The rollout you may have seen in the news is happening in England. Wales is developing its own self-sampling programme, which is expected to roll out later in 2026.
So what exactly is happening, what does the evidence tell us, and what does it mean if you live in Wales?
What is HPV self-sampling?
Let’s start with the basics.
HPV stands for human papillomavirus. It is an extremely common virus, and most people will come into contact with it at some point in their lives.
Certain types of HPV, known as high-risk HPV, can cause changes to the cells of the cervix. If these changes persist and are not identified and managed, they can, over time, develop into cervical cancer.
This is why cervical screening now looks for high-risk HPV.
In Wales, HPV testing has been the primary cervical screening test since 2018.
With self-sampling, instead of a healthcare professional taking a sample from your cervix using a speculum, you collect a sample yourself from inside the vagina using a swab.
That sample is then sent to a laboratory where it is tested for high-risk HPV.
It is important to understand that this is an HPV test. It isn’t quite the same thing as doing a traditional cervical screening sample yourself.
So, is self-sampling as good as having a cervical screening test?
This is one of the obvious questions.
The evidence so far is encouraging.
Research has shown that HPV testing using self-collected vaginal samples can be an effective way of detecting high-risk HPV, and women generally find self-sampling acceptable.
One of the most important UK studies has been the YouScreen study in England. It looked at offering HPV self-sampling to people who had not attended cervical screening and found that offering self-sampling could increase participation, including among groups who have historically been less likely to take part.
And this is really the key point.
The purpose of self-sampling isn’t necessarily to replace the way everyone currently has their cervical screening.
It is about finding another way to reach people who might otherwise not be screened at all.
That could make a very real difference.
Who is being offered self-sampling in England?
The rollout in England has now begun, but it is not currently a replacement for routine cervical screening for everyone.
It is being introduced in phases and is initially aimed at women and people with a cervix aged 30 to 65 who have not attended cervical screening following previous invitations.
It is an invitation-only programme.
So this isn’t currently a situation where everyone is going to receive a home testing kit instead of their usual screening appointment.
The aim is to reach people who are under-screened – particularly those who have repeatedly not taken up their invitations.
And I think that makes a lot of sense.
If you are already attending your cervical screening appointments regularly, there is currently no reason to assume that you need to change how you are screened simply because self-sampling is now available.
What happens if HPV is detected?
This is really important.
A self-sample can tell us whether high-risk HPV is present.
It cannot tell us whether there are abnormal cells on the cervix.
So if high-risk HPV is detected, you will need further assessment.
You would be invited for a follow-up cervical screening appointment where a trained healthcare professional takes a sample from the cervix so that the cervical cells can be examined.
Depending on the result of that sample, you may then need further monitoring or referral for assessment such as colposcopy.
So self-sampling does not necessarily mean avoiding a clinical examination altogether.
It is another way of getting people into the screening pathway.
And if you receive a positive HPV result from a self-sample, it is really important that you attend the follow-up appointment when invited.
What happens if HPV isn’t detected?
This is the reassuring part.
If high-risk HPV isn’t detected, your risk of developing significant cervical cell changes in the near future is very low.
In Wales, if HPV isn’t found during routine screening, you are generally invited for screening again in five years.
That longer interval can sometimes seem surprising, but it reflects how much cervical screening has changed.
We now know that testing for high-risk HPV is a very effective way of identifying people who are at increased risk of developing cervical cell changes.
So a negative HPV result is genuinely reassuring.
Why are we introducing self-sampling?
Because not everyone finds cervical screening easy.
And I think we need to acknowledge that.
As a gynaecologist, I see women who are anxious about cervical screening for lots of different reasons.
Some have experienced pain.
Some have had a previous difficult examination.
Some have experienced trauma.
Some feel embarrassed.
Some find intimate examinations particularly difficult because of sensory sensitivities or anxiety.
And for others, it is simply the practicalities.
Work.
Childcare.
Transport.
Appointments that don’t fit around their lives.
None of these things mean someone doesn’t care about their health.
Sometimes the system simply hasn’t made it easy for them to take part.
Self-sampling removes some of those barriers.
You can collect the sample yourself, in your own home, without a speculum examination.
For some women, that could be the difference between being screened and not being screened at all.
Could self-sampling increase cervical screening uptake?
This is probably the most exciting part of the evidence.
Studies have shown that offering HPV self-sampling can encourage some people who have previously not attended cervical screening to participate.
The UK National Screening Committee reviewed the evidence and recommended that cervical screening programmes across the UK could offer self-sampling to people who never or rarely attend routine screening. It specifically identified the potential to increase participation and reduce health inequalities.
And that is important because cervical screening only works if people take part.
A screening test sitting unopened at home or an appointment that is repeatedly missed cannot prevent cervical cancer.
If self-sampling makes screening accessible to someone who has previously struggled to attend, that is a very positive thing.
So what does this mean if you live in Wales?
This is where things get a little confusing because much of the news you are currently seeing is about England.
Wales has its own cervical screening programme and its own arrangements.
The UK National Screening Committee’s recommendation applies across the UK, but each nation’s screening programme decides how it will implement self-sampling.
The Welsh Government confirmed in March 2026 that Cervical Screening Wales is developing an at-home, self-collected screening model, with rollout planned for later in 2026.
The initial focus will be on women who rarely or never take up their offer of cervical screening.
So, if you live in Wales:
Self-sampling is coming.
But the English rollout does not mean that you can currently order an English NHS kit if you live in Wales.
The Welsh programme will set out how the service will work here, who will initially be eligible and how the kits and follow-up pathway will operate.
Does this mean I should wait for self-sampling?
No.
This is probably the most important message I want people to take away from all of this.
If you have received an invitation for cervical screening, please go.
Don’t put off your screening appointment because you’ve heard that home testing is coming.
The initial self-sampling programme is being introduced specifically to try to reach people who are currently under-screened.
It isn’t a reason for people who already attend screening to stop doing so.
Cervical screening remains one of the most effective ways we have of preventing cervical cancer.
What if I’ve avoided cervical screening because I’m worried about the examination?
Please don’t feel embarrassed about saying that.
As a gynaecologist, I would much rather know that someone is anxious, has experienced pain previously, has had a traumatic experience, or simply doesn’t feel comfortable with a speculum examination.
There are things that can sometimes help.
You can talk to the healthcare professional beforehand.
You can ask questions.
You can ask for a smaller speculum where appropriate.
You can ask them to explain what they are doing before they do it.
You can agree on a signal to stop.
And you can tell them if you’ve had a previous difficult experience.
A cervical screening appointment should not feel like something that is simply being done to you.
You should feel involved in what is happening.
And if self-sampling eventually makes screening more accessible for you, that is exactly what it is there to do.
What if I’ve had the HPV vaccine?
You should still attend cervical screening.
The HPV vaccine provides excellent protection against the HPV types that cause many cervical cancers, and it has already had a significant impact on HPV infection and cervical disease.
But it doesn’t protect against every HPV type that can cause cervical cancer.
So even if you were vaccinated as a teenager, you should still take up your screening invitation when you are eligible.
What if I’ve only ever had one sexual partner?
You should still attend.
HPV is extremely common and can be passed through intimate skin-to-skin contact.
Having had few sexual partners doesn’t mean that your risk is zero.
And if HPV is detected, it doesn’t tell us when you acquired it or who you acquired it from.
A positive HPV result is not evidence of infidelity.
What if I’ve had normal screening results before?
You should still attend when invited.
Previous normal results are reassuring, but they don’t mean that you never need screening again.
Screening works because it is repeated at appropriate intervals.
It is about identifying risk before cervical cancer develops.
Symptoms that should be checked
Whether you have recently had a cervical screening test, regularly attend your appointments, or have had a normal HPV result, you should still speak to your GP or another healthcare professional if you develop new or unusual symptoms.
These can include:
- Bleeding between periods
- Bleeding after sex
- Bleeding after the menopause
- Periods that become unusually heavy or different from your normal pattern
- Unusual or persistent vaginal discharge
- Pain during sex
- Persistent pelvic or lower abdominal pain
There are many different reasons why these symptoms can happen, and having one of them does not mean that you have cervical cancer. Often, there will be a much more straightforward explanation.
However, it is important not to assume that a recent normal screening result means these symptoms can be ignored.
Cervical screening looks for high-risk HPV in people who do not have symptoms. If you develop symptoms that are new, persistent or concerning to you, they need to be assessed in their own right.
So, please don’t wait for your next screening appointment if something doesn’t feel right.
Know your normal. If something changes and you’re worried about it, get it checked.
The bottom line
HPV self-sampling is a really positive development.
Not because the traditional cervical screening test has suddenly become unnecessary, but because we are recognising that one approach doesn’t work for everyone.
For some women, being able to take a sample at home may be the thing that finally allows them to take part in screening.
And if it means reaching women who have repeatedly missed screening, it has the potential to reduce inequalities and prevent more cervical cancers.
Here in Wales, self-sampling is expected later in 2026, with the initial focus on people who rarely or never attend screening.
But please don’t wait for it if you already have a cervical screening appointment.
If you’re invited, please go.
If you’ve missed an appointment, arrange another one.
If you’re worried about the examination, tell your healthcare professional.
And if cervical screening has been something you’ve avoided because the usual process doesn’t work for you, keep an eye out for information from Cervical Screening Wales about the new self-sampling option.
The important thing isn’t whether you have your screening test at home or in a clinic.
The important thing is that you have it.
Because cervical screening isn’t about finding cancer.
It’s about preventing it.
